RNA Details
Disease Name
kidney diseases
Tissue
kidney
RNA Symbol
mir-101a
RNA ID
RNA Type
miRNA
Alteration Pattern
down regulation
Species
mus musculus
Detection Methods
qPCR; dual-luciferase reporter assay; immunohistochemistry
Target
KDM3A
Pathway
TGF-BETA SIGNALING PATHWAY
PubMed ID
Title
Upregulation of miR-101a Suppresses Chronic Renal Fibrosis by Regulating KDM3A via Blockade of the YAP-TGF-beta-Smad Signaling Pathway
Year
2020
Function
miR-101a could potentially slow down chronic renal fibrosis by the inactivation of the yap-diabetic nephropathy-smad signaling pathway via KDM3A.